2025 Viral Hepatitis National Progress Report

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In alignment with CDC’s Division of Viral Hepatitis 2025 Strategic Plan, the Viral Hepatitis National Progress Report provides information on progress toward 2025 goals for new viral hepatitis infections and viral hepatitis-related deaths, overall and for key populations.

CDC 2025 National Viral Hepatitis Progress Report cover

Progress

Ten objective indicators assess progress toward achieving key viral hepatitis goals.

a green square with a checkmark in the center

Met or exceeded current annual target

a yellow square with a right pointing arrow in the center

Moving toward annual target, but annual target was not fully met

a red square with an X in the center

Has moved away from annual target or has not changed

Ten objective indicators assess progress toward achieving key viral hepatitis goals.
2017 Baseline Data 2023 Data 2025 Goal/annual target* Trend 2023 Status
Hepatitis A
Reduce estimated† new hepatitis A virus infections by ≥40% 6,700 3,300 4,000 micro trend line, depicting trends toward, inline, or away from target X on red, indicating 'Not met—no change or moved away from annual target'
Hepatitis B
Reduce estimated† new hepatitis B virus infections by ≥20% 22,200 14,400 18,000 micro trend line, depicting trends toward, inline, or away from target Check on Green, indicating 'Met or exceeded current annual target'
Reduce reported rate‡ of new hepatitis B virus infections among persons who inject drugs by ≥25% 1.40 0.60 1.00 micro trend line, depicting trends toward, inline, or away from target Check on Green, indicating 'Met or exceeded current annual target'
Reduce reported rate‡ of hepatitis B-related deaths by ≥20% 0.46 0.44 0.37 micro trend line, depicting trends toward, inline, or away from target X on red, indicating 'Not met—no change or moved away from annual target'
Reduce reported rate‡ of hepatitis B-related deaths among non-Hispanic Asian/Pacific Islander persons by ≥25% 2.45 2.20 1.84 micro trend line, depicting trends toward, inline, or away from target X on red, indicating 'Not met—no change or moved away from annual target'
Hepatitis C
Reduce estimated† new hepatitis C virus infections by ≥20% 44,700 69,000 35,000 micro trend line, depicting trends toward, inline, or away from target X on red, indicating 'Not met—no change or moved away from annual target'
Reduce reported rate‡ of new hepatitis C virus infections among persons who inject drugs by ≥25% 2.30 2.60 1.70 micro trend line, depicting trends toward, inline, or away from target X on red, indicating 'Not met—no change or moved away from annual target'
Reduce reported rate‡ of hepatitis C-related deaths by ≥20% 4.13 2.52 3.00 micro trend line, depicting trends toward, inline, or away from target Check on Green, indicating 'Met or exceeded current annual target'
Reduce reported rate‡ of hepatitis C-related deaths among non-Hispanic American Indian/Alaska Native persons by ≥30% 10.24 7.75 7.17 micro trend line, depicting trends toward, inline, or away from target X on red, indicating 'Not met—no change or moved away from annual target'
Reduce reported rate‡ of hepatitis C-related deaths among non-Hispanic Black persons by ≥30% 7.03 4.03 4.92 micro trend line, depicting trends toward, inline, or away from target Check on Green, indicating 'Met or exceeded current annual target'
* Annual targets assume a constant (linear) rate of change from the observed baseline (2017) to the 2025 goal (2023 data year).
† The number of estimated viral hepatitis infections was determined by multiplying the number of reported cases by a factor that adjusted for underascertainment and underreporting ( CDC 2023 Viral Hepatitis Surveillance Report and Klevens et al., 2014)1.
‡ Per 100,000 population.
Persons aged 18–40 years were used as a proxy for persons who inject drugs.

Related content

2023 Viral Hepatitis Surveillance Report
See the 2023 Viral Hepatitis Surveillance Report, published by CDC’s Viral Hepatitis Program
Viral Hepatitis Surveillance Reports
See list of all viral hepatitis surveillance reports, surveillance guidelines, and national progress
Division of Viral Hepatitis: 2025 Strategic Plan
Explore the CDC’s 2025 goals and strategies to reduce hepatitis infections, viral hepatitis-related.
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Content Source:
Division of Viral Hepatitis
  1. Klevens RM, Liu S, Roberts H, et al. Estimating acute viral hepatitis infections from nationally reported cases. Am J Public Health 2014;104:482. PMC3953761.