Table 2.2 ¨C Acute Hepatitis B: Cases & Rates by Demographics

Key points

During 2023, rates of reported cases of acute hepatitis B were highest among persons aged 40–49 and 50–59 years, males, non-Hispanic Black persons, and in US Department of Health and Human Services Region 4 (Alabama, Florida, Georgia, Kentucky, Mississippi, North Carolina, South Carolina, and Tennessee).
CDC 2023 Hepatitis B Surveillance Report

Numbers and rates* of reported cases† of acute hepatitis B, by demographic characteristics — United States, 2019–2023

The numbers and rates of reported cases of acute hepatitis B by demographic characteristics (age, sex, race/ethnicity, urbanicity, and US Department of Health and Human Services region) for 2019–2023. The first column lists the demographic characteristics. Each year has two columns of data; the first column displays the number of reported acute hepatitis B cases, and the second column displays the rates of reported acute hepatitis B cases per 100,000 population for each demographic category by year.
Characteristic 2019 No. 2019 Rate* 2020 No. 2020 Rate* 2021 No. 2021 Rate* 2022 No. 2022 Rate* 2023 No. 2023 Rate*
Total§ 3,192 1.0 2,157 0.7 2,045 0.6 2,126 0.6 2,214 0.7
Age (years)
0–19 13 0.0 20 0.0 20 0.0 14 0.0 21 0.0
20–29 218 0.5 160 0.4 166 0.4 180 0.4 211 0.5
30–39 801 1.8 443 1.0 405 0.9 340 0.7 345 0.7
40–49 1,067 2.7 685 1.7 641 1.6 578 1.4 583 1.4
50–59 675 1.6 502 1.2 439 1.0 518 1.2 490 1.2
≥60 418 0.6 346 0.5 374 0.5 496 0.6 564 0.7
Sex
Male 2,021 1.3 1,297 0.8 1,215 0.7 1,280 0.8 1,370 0.8
Female 1,169 0.7 857 0.5 829 0.5 843 0.5 841 0.5
Race/ethnicity
American Indian/Alaska Native, non-Hispanic 15 0.6 10 0.4 11 0.4 10 0.4 13 0.5
Asian/Pacific Islander, non-Hispanic 63 0.3 52 0.2 48 0.2 59 0.3 78 0.4
Black, non-Hispanic 382 0.9 309 0.7 368 0.9 414 1.0 466 1.1
White, non-Hispanic 2,045 1.0 1,391 0.7 1,205 0.6 1,206 0.6 1,150 0.6
Hispanic 215 0.4 155 0.3 224 0.4 258 0.4 337 0.5
Other 93 n/a 73 n/a 63 n/a 62 n/a 77 n/a
Urbanicity
Urban 2,504 0.9 1,714 0.6 1,701 0.6 1,812 0.6 1,928 0.7
Rural 519 1.2 402 0.9 339 0.7 314 0.7 283 0.6
HHS region**
Region 1: Boston 112 0.8 60 0.4 51 0.4 56 0.4 76 0.5
Region 2: New York 163 0.6 89 0.3 94 0.3 98 0.3 99 0.3
Region 3: Philadelphia 277 0.9 192 0.6 161 0.5 203 0.6 162 0.5
Region 4: Atlanta 1,458 2.2 1,125 1.7 1,122 1.7 1,139 1.7 1,245 1.8
Region 5: Chicago 612 1.2 321 0.6 259 0.5 239 0.5 196 0.4
Region 6: Dallas 202 0.5 155 0.4 149 0.3 148 0.3 161 0.4
Region 7: Kansas City 68 0.6 36 0.3 35 0.2 34 0.2 49 0.3
Region 8: Denver 55 0.5 35 0.3 25 0.2 45 0.4 32 0.3
Region 9: San Francisco 163 0.3 85 0.2 96 0.2 120 0.2 154 0.3
Region 10: Seattle 82 0.6 59 0.4 53 0.4 44 0.3 40 0.3
Table 2.2 Data
table-2.2
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Source: CDC, National Notifiable Diseases Surveillance System.

* Rates per 100,000 population. Beginning in 2021, single-race population estimates are used for rate calculations. For prior years, bridged-race population estimates are used. When comparing the 2023 rates by race/ethnicity to prior years, differences may be due to the changes in denominator and should be interpreted with caution (see Technical Notes).

† Reported confirmed cases. For the case definition, see .

§ Numbers reported in each category may not add up to the total number of reported cases in a year due to cases with missing data.

¶ Urbanicity was categorized according to the 2013 National Center for Health Statistics (NCHS) urban-rural classification scheme for counties and county-equivalent entities. Large central metro, large fringe metro, medium metro, and small metro counties were grouped as urban. Micropolitan and noncore counties were grouped as rural.

** US Department of Health and Human Services regions were categorized according to the grouping of states and US territories assigned under each of the 10 . For the purposes of this report, regions with US territories (Region 2 and Region 9) contain data from states only.

n/a: Not applicable. Rate cannot be calculated due to lack of corresponding denominator.

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