What to know
- Presentation Day/Time: Thursday, April 24, 9:00–10:25 am
- Presenter: Mila Shakya, DPhil, MPH, MBSS, EIS officer assigned to the National Center for Immunization and Respiratory Diseases, Coronavirus and Other Respiratory Viruses Division

What did we do?
- We assessed incidence and risk factors for symptomatic human metapneumovirus (hMPV) infection in a community-based cohort study in Oregon and Washington.
What did we find?
- Overall, 307/3,557 participants (8.6%) had symptomatic hMPV.
- Those with hMPV most frequently reported cough (80.1%), nasal congestion (71.7%) and sore throat (38.1%).
- Among 254 (82.7%) hMPV-positive participants with complete information, 69 (27.2%) missed work/school, 19 (7.5%) had medically-attended illness, and 2 (0.8%) were hospitalized.
- Average incidence of symptomatic hMPV infection was 7.5 per 100 persons per year.
- Incidence was highest during March-May and among children aged 2–5 years, and clustered in households.
Why does it matter?
- Approximately 7% of persons aged <50 years may experience symptomatic hMPV infection annually.
- Although most illnesses are mild, a substantial proportion result in absenteeism, highlighting the impact that even mild infection can have on daily activities, including work, school, and child care facility attendance.
- Understanding hMPV epidemiology can guide surveillance definitions, clinical testing, and prioritization of prevention strategies.
***This presentation has updated data that will be shared at the EIS Conference.
Abstract Category: Human Metapneumovirus (hMPV)