Monitoring Group A Streptococcus Infections Using Emergency Department Visit Data ¡ª United States, 2019¨C2022

What to know

  • Presentation Day/Time: Friday, April 25, 10:55 am–12:20 pm
  • Presenter: Joe Silva, PhD, ScM, EIS officer assigned to the National Center for Immunization and Respiratory Diseases, Division of Bacterial Diseases
Joe Silva, PhD, ScM

What did we do?

  • To support timely public health recommendations, we assessed the potential for near real-time weekly emergency department (ED) visit data from the National Syndromic Surveillance Program (NSSP) to provide earlier awareness of increases in invasive group A Streptococcus (GAS) infections.

What did we find?

  • During 2019–2022, 9,872 iGAS cases were observed in CDC's Active Bacterial Core surveillance (ABCs).
  • From NSSP, there were 13,212 ED visits for iGAS, 6,189,093 ED visits for pharyngitis, and 34,670 ED visits for scarlet fever in the same period.
  • ED iGAS visits were correlated with ABCs iGAS cases and mirrored weekly fluctuations in incidence, including peaks during winter months.
  • ABCs iGAS cases were also correlated with pharyngitis and scarlet fever ED visits.
  • Correlation results were similar for all age groups and children.

Why does it matter?

  • iGAS infections are associated with up to 20% mortality.
  • In 2022, U.S. iGAS infections reached a 20-year high according to CDC's ABCs, an active, population-, and laboratory-based surveillance system that monitors invasive infections.
  • Our assessment found that ED visits correlated well with ABCs iGAS cases, demonstrating NSSP's utility in providing rapid awareness of GAS disease activity, including for non-invasive GAS infections not tracked by ABCs.
  • Early detection through NSSP may facilitate timely recommendations for healthcare providers, state and territorial health departments, and the public.

***This presentation has updated data that will be shared at the EIS Conference.

Abstract Category: Group A Strep