Increase in Invasive Group A Streptococcal Disease in Alaska, January¨CJune 2024

What to know

  • Presentation Day/Time: Friday, April 25, 10:55 am–12:20 pm
  • Presenter: Victoria Balta, PhD, MPH, EIS officer assigned to the National Center for Emerging and Zoonotic Infectious Diseases, Division of Infectious Disease Readiness and Innovation
Victoria Balta, PhD, MPH

What did we do?

  • In response to anecdotal clinician reports, we evaluated whether an increase in invasive group A Streptococcusal (GAS) disease occurred in Alaska during 2024 and compared changes among subpopulations.

What did we find?

  • During January–June 2024, 145 invasive GAS cases were reported in Alaska, compared with an average of 76 cases during January–June of 2016–2023.
  • There was a significant increase across all age groups and localities in Alaska, however, the increase was most notable among people aged ≥60 years and Native Hawaiian/Pacific Islander people.
  • Certain underlying medical conditions such as diabetes, chronic renal failure, and undergoing kidney dialysis increased among cases while certain risk factors decreased in 2024.
  • Emm type 1 isolates increased from 6% during 2016–2023 to 23% during 2024, and emm type 53 isolates increased from <1% to 29% during 2024.

Why does it matter?

• An increase in invasive GAS disease occurred in Alaska during early 2024, especially among certain subpopulations, and appeared to be associated with rise of emm type 1 and the emergence of emm type 53 in the state.

• These preliminary data require further investigation to elucidate factors associated with the increase of invasive GAS disease and develop suitable public health interventions.

Abstract Category: Group A Strep